Pt　nanoparticles　and　a　CeMnOx　composite　were　loaded　on　the　surface　of　the　natural　diatomite　material　to　generate　the　Pt/CeMnOx/diatomite　using　the　redox　precipitation　and　impregnation　methods.　The　physicochemical　properties　of　the　catalysts　were　characterized　by　means　of　various　techniques.　The　catalytic　properties　and　resistance　to　H2O　and　SO2　of　the　catalysts　were　measured　for　the　oxidation　of　typical　volatile　organic　compounds　(i.e.,　toluene　and　ethyl　acetate).　Among　all　of　the　as-prepared　samples,　Pt/CeMnOx/diatomite　exhibited　the　highest　catalytic　activity:　the　temperatures　(T-90%)　at　a　toluene　or　ethyl　acetate　conversion　of　90%　were　230　and　210　degrees　C　at　a　space　velocity　(SV)　of　20,000　mL　g(-1)　h(-1),　respectively,　and　the　turnover　frequency　(TOFPt)　at　220　degrees　C　was　1.04　mu　mol/(g(cat)　s)　for　ethyl　acetate　oxidation　and　1.56　mu　mol/(g(cat)　s)　for　toluene　oxidation.　In　particular,　this　sample　showed　a　superior　catalytic　activity　for　ethyl　acetate　oxidation　at　low　temperatures,　with　its　T-50%　being　185　degrees　C　at　SV　=　20,000　mL　g(-1)　h(-1).　In　addition,　the　Pt/CeMnOx/diatomite　sample　possessed　good　sulfur　dioxide　resistance　during　the　toluene　oxidation　process.　In　the　presence　of　SO2,　some　of　the　SO2　molecules　were　adsorbed　on　diatomite,　which　protected　the　active　sites　from　being　poisoned　by　SO2　to　a　certain　extent.　The　pathways　of　ethyl　acetate　and　toluene　oxidation　over　Pt/CeMnOx/diatomite　or　Pt/CeMnOx　were　as　follows:　The　C-C　and　C-O　bonds　in　ethyl　acetate　are　first　broken　to　form　the　CH3CH2O*　and　CH3CO*　species　or　toluene　is　first　oxidized　to　benzaldehyde　and　benzoic　acid,　and　all　of　these　intermediates　are　then　converted　to　CO2　and　H2O.　This　work　can　provide　a　strategy　to　develop　efficient　catalysts　with　high　catalytic　activity,　durability,　low　cost,　and　easy　availability　under　actual　working　conditions.