To　accurately　simulate　and　realize　the　multiple　input　multiple　output　(MIMO)　loop　control　of　municipal　solid　waste　incineration　(MSWI)　process,　a　distributed　hardware-in-the-loop　simulation　platform　consisting　of　a　real　device　layer　and　a　virtual　object　layer　is　developed　based　on　the　actual　industrial　process.　The　mechanism　model　is　qualitatively　described,　and　a　data-driven　virtual　process　object　model　in　terms　of　loop　control　is　established.　The　software　subsystems　of　the　platform　and　their　cooperative　operation　mode　are　designed　based　on　the　control　requirement.　The　hardware　and　software　of　the　proposed　platform　are　built　and　experimentally　verified　based　on　actual　industrial　data.　The　results　show　that　the　platform　provides　a　reliable　engineering　verification　environment　for　the　intelligent　modeling　and　the　control　algorithm　of　MSWI　process.　©　2023　Acta　Simulata　Systematica　Sinica.　All　rights　reserved.