In　this　paper,　the　seismic　reduction　and　isolation　measures　are　first　proposed　by　setting　a　segmented　isolation　layer　between　the　diaphragm　wall　and　the　side　wall　of　the　station　structure.　Although　the　segmented　isolation　layer　can　effectively　improve　the　stress　state　of　the　side　wall　and　slabs,　the　seismic　reduction　effect　of　the　middle　column　is　not　obvious.　In　order　to　improve　the　overall　seismic　performance　of　the　station　structure,　the　reduction　measures　by　combining　the　segmented　isolation　layer　and　new　type　bearing　of　the　middle　column　are　then　proposed.　At　the　same　time　of　inserting　the　isolation　layer　between　the　diaphragm　wall　and　the　structure,　the　sliding　bearing　at　the　top　of　the　column　is　set　up　to　reduce　the　vibration.　The　results　show　that　the　segmented　isolation　layer　can　significantly　reduce　the　internal　force　and　damage　at　the　top,　bottom　and　side　wall　joints.　In　addition,　the　combined　measures　of　segmented　isolation　layer　and　sliding　bearing　at　the　top　of　the　column　can　effectively　reduce　the　seismic　damage　of　the　middle　column.　The　damage　of　the　connection　between　the　top　plate,　the　middle　plate　and　the　middle　column　can　be　significantly　decreased.