So　far,　almost　all　studies　have　concentrated　on　the　compressive　performance　of　fully　loaded　concrete-filled　double-skin　steel　tubular　(CFDST)　columns,　but　there　have　been　few　studies　on　partially　loaded　CFDST　columns,　and　the　difference　in　their　behavior　remains　unclear.　Thus,　by　focusing　on　the　mechanical　behavior　of　circular　CFDST　columns　under　different　loading　arrangements,　this　paper　conducts　a　comparative　study　on　circular　axially　loaded　CFDST　columns　based　on　the　author’s　previous　experimental　results.　A　total　of　28　experiments　were　conducted,　in　which　14　fully　and　14　partially　loaded　specimens　were　tested.　The　influence　law　of　crucial　parameters　on　the　compressive　behavior　of　CFDST　specimens　with　two　different　loading　arrangements　were　compared　and　the　results　were　discussed.　It　is　shown　that　when　the　void　ratio　is　0　and　0.2,　the　ultimate　strength　of　partially　loaded　CFDST　columns　is　greater　than　that　of　fully　loaded　ones,　but　the　results　are　opposite　for　the　columns　with　the　void　ratios　of　0.4　and　0.6.　Subsequently,　based　on　the　experimental　data,　a　finite　element　analysis　(FEA)　model　was　developed　and　used　to　ascertain　the　compressive　behavior　of　CFDST　columns　with　two　different　loading　arrangements.　The　results　suggested　that,　at　the　beginning　of　the　loading　phase,　the　outer　tube　of　partially　loaded　CFDST　columns　provided　a　certain　lateral　confining　stress　to　the　concrete,　while　the　lateral　confining　stress　of　fully　loaded　CFDST　columns　fluctuated　around　zero.　The　axial　load　of　the　inner　tube　of　fully　loaded　CFDST　columns　first　increased　linearly　and　then　remained　almost　unchanged.　Due　to　the　existence　of　friction,　the　inner　tube　of　partially　loaded　CFDST　columns　also　undertook　a　certain　axial　load,　which　first　increased　and　then　decreased　to　zero.　©　2023　by　the　authors.