In　this　paper,　intermittent　wavy　microchannels　are　designed　and　fabricated　by　MEMS　technique.　The　flow　boiling　heat　transfer　characteristics　of　intermittent　wavy　microchannels　are　experimentally　investigated　using　acetone　as　the　working　fluid　under　the　aid　of　high-speed　synchronous　measurement　system.　The　flow　pattern,　heat　transfer　coefficient　and　bottom　wall　temperature　distribution　are　analyzed　as　compared　to　the　conventional　rectangular　microchannels.　The　experimental　results　show　that　the　stable　annular　flow　can　be　maintained　near　the　outlet　of　the　intermittent　wavy　microchannels　and　the　local　dry-out　is　postponed　effectively.　The　unique　wall　structure　can　promote　the　boiling　heat　transfer　performance　so　that　about　70%　enhancement　of　heat　transfer　coefficient　can　be　achieved　with　intermittent　wavy　microchannels　compared　to　the　rectangular　microchannels.　The　bottom　wall　temperature　difference　of　the　intermittent　wavy　microchannels　is　lower　than　the　rectangular　microchannels　under　the　same　condition　indicating　that　a　better　temperature　uniformity　can　be　provided.　©　2020,　Science　Press.　All　right　reserved.