Current　research　on　the　fatigue　properties　of　degradable　zinc　alloy　stents　has　not　yet　considered　the　issue　of　the　fatigue　life　changing　with　material　properties　during　the　dynamic　degradation　process.　Therefore,　in　this　paper,　we　established　a　fatigue　damage　algorithm　to　study　the　fatigue　problem　affected　by　the　changing　of　material　properties　during　the　dynamic　degradation　process　of　the　stent　under　the　action　of　pulsating　cyclic　loading.　Three　models:　the　dynamic　degradation　model,　the　dynamic　degradation　model　under　pulsating　cyclic　loading,　and　the　coupled　model　of　fatigue　damage　and　dynamic　degradation,　were　developed　to　verify　the　effect　of　fatigue　damage　on　stent　life.　The　results　show　that　fatigue　damage　leads　to　a　deeper　degree　of　inhomogeneous　degradation　of　the　stent,　which　affects　the　service　life　of　the　stent.　Fatigue　damage　is　a　factor　that　cannot　be　ignored.　Therefore,　when　studying　the　mechanical　properties　and　lifetime　of　degradable　stents,　incorporating　fatigue　damage　into　the　study　can　help　more　accurately　assess　the　lifetime　of　the　stents.