Graphene　oxide　(GO)　membrane　has　been　considered　as　a　promising　approach　for　harvesting　pure　water　from　various　wastewater　to　deal　with　the　current　water　shortage　issue,　arising　from　its　distinctive　2D　channel　features.　However,　the　narrow　interlayer　distance　(0.75　Å)　of　GO　nanosheets　hampers　the　utilization　of　GO　membranes　for　dye　wastewater　treatment,　which　demands　superior　water　permeance,　high　dyes　rejection,　and　low　salts　rejection.　Herein,　an　in-situ　anchored　nanoparticle　strategy　is　designed　to　fabricate　Fe(OH)3@GO　membrane　to　enlarge　the　interlayer　distance　via　the　uniform　distributed　Fe(OH)3　nanoparticles.　Benefiting　from　the　in-situ　transformation　of　Fe3+　into　positively　charged　Fe(OH)3　nanoparticles,　the　interlayer　distance　of　GO　membranes　can　be　tailored　via　changing　the　Fe:　GO　mass　ratio　and　hydrolysis　time.　The　optimized　Fe(OH)3@GO　membrane　realizes　a　superior　water　permeance　of　∼90.9　LMH/bar　(∼19-fold　enhancement　compared　with　GO　membranes),　with　＞99%　and　＜4%　rejection　to　Evans　blue　(EB)　and　NaCl,　respectively.　Thus,　the　membrane　can　be　applied　for　dye　desalination　and　can　be　stably　running　for　85　h.　Considering　the　facile　and　efficient　2D　channel　tunability,　our　strategy　provides　an　innovative　approach　for　construction　of　high-performance　2D　membranes.　©　2024　Elsevier　B.V.