As　an　intelligent　flexible　material　with　multi-field　coupling　characteristics,　the　preparation　technology,　performance　characterization,　and　structural　application　of　hydrogels　have　been　rapidly　developed.Based　on　a　detailed　analysis　of　the　constitutive　theory　and　structural　design　of　hydrogels,　this　paper　proposes　the　basic　methods　and　paradigms　of　computational　multi-field　coupling　mechanics　of　hydrogels.At　the　microscopic　scale,　a　coarse-grained　molecular　dynamics　model　of　hydrogel　has　been　developed.The　coarse-grained　force　field　was　determined　by　using　a　machine　learning　method.At　the　macroscale,　based　on　the　recently　developed　constitutive　models　for　isotropic　hydrogel　incorporating　the　effects　of　chain　entanglements　and　anisotropic　hydrogel　reinforced　by　fibers,　a　coupled　finite　element　method　is　presented　to　investigate　the　chemo-mechanical　coupling　behavior　of　the　designed　intelligent　structures　of　hydrogels.It　is　pointed　out　that　computational　multi-field　coupled　mechanics　will　become　the　main　analysis　method　for　hydrogel　structures,　which　contributes　to　the　property　design　and　engineering　application　of　this　kind　of　intelligent　flexible　materials.　©　2024　Editorial　Office　of　Chinese　Journal　of　Computational　Mechanics.　All　rights　reserved.