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Author:

Li, Jianqiang (Li, Jianqiang.) | Zhu, Chujie (Zhu, Chujie.) | Zhao, Mingming (Zhao, Mingming.) | Xu, Xi (Xu, Xi.) | Zhao, Linna (Zhao, Linna.) | Cheng, Wenxiu (Cheng, Wenxiu.) | Liu, Suqin (Liu, Suqin.) | Zou, Jingchen (Zou, Jingchen.) | Yang, Ji-Jiang (Yang, Ji-Jiang.) | Yin, Jian (Yin, Jian.)

Indexed by:

Scopus SCIE

Abstract:

This paper presents an eye image segmentation-based computer-aided system for automatic diagnosis of ocular myasthenia gravis (OMG), called OMGMed. It provides great potential to effectively liberate the diagnostic efficiency of expert doctors (the scarce resources) and reduces the cost of healthcare treatment for diagnosed patients, making it possible to disseminate high-quality myasthenia gravis healthcare to under-developed areas. The system is composed of data pre-processing, indicator calculation, and automatic OMG scoring. Building upon this framework, an empirical study on the eye segmentation algorithm is conducted. It further optimizes the algorithm from the perspectives of "network structure" and "loss function", and experimentally verifies the effectiveness of the hybrid loss function. The results show that the combination of "nnUNet" network structure and "Cross-Entropy + Iou + Boundary" hybrid loss function can achieve the best segmentation performance, and its MIOU on the public and private myasthenia gravis datasets reaches 82.1% and 83.7%, respectively. The research has been used in expert centers. The pilot study demonstrates that our research on eye image segmentation for OMG diagnosis is very helpful in improving the healthcare quality of expert doctors. We believe that this work can serve as an important reference for the development of a similar auxiliary diagnosis system and contribute to the healthy development of proactive healthcare services.

Keyword:

ocular myasthenia gravis proactive healthcare service eye image segmentation empirical study

Author Community:

  • [ 1 ] [Li, Jianqiang]Beijing Univ Technol, Fac Informat Technol, Beijing 100124, Peoples R China
  • [ 2 ] [Zhu, Chujie]Beijing Univ Technol, Fac Informat Technol, Beijing 100124, Peoples R China
  • [ 3 ] [Xu, Xi]Beijing Univ Technol, Fac Informat Technol, Beijing 100124, Peoples R China
  • [ 4 ] [Zhao, Linna]Beijing Univ Technol, Fac Informat Technol, Beijing 100124, Peoples R China
  • [ 5 ] [Cheng, Wenxiu]Beijing Univ Technol, Fac Informat Technol, Beijing 100124, Peoples R China
  • [ 6 ] [Liu, Suqin]Beijing Univ Technol, Fac Informat Technol, Beijing 100124, Peoples R China
  • [ 7 ] [Zou, Jingchen]Beijing Univ Technol, Fac Informat Technol, Beijing 100124, Peoples R China
  • [ 8 ] [Zhao, Mingming]Beijing Hosp, Dept Neurol, Beijing 100730, Peoples R China
  • [ 9 ] [Yin, Jian]Beijing Hosp, Dept Neurol, Beijing 100730, Peoples R China
  • [ 10 ] [Yang, Ji-Jiang]Tsinghua Univ, Tsinghua Natl Lab Informat Sci & Technol, Beijing 100084, Peoples R China

Reprint Author's Address:

  • [Yin, Jian]Beijing Hosp, Dept Neurol, Beijing 100730, Peoples R China;;[Yang, Ji-Jiang]Tsinghua Univ, Tsinghua Natl Lab Informat Sci & Technol, Beijing 100084, Peoples R China;;

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Source :

BIOENGINEERING-BASEL

Year: 2024

Issue: 6

Volume: 11

4 . 6 0 0

JCR@2022

Cited Count:

WoS CC Cited Count:

SCOPUS Cited Count:

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 2

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