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Author:

Mu, Zhenxia (Mu, Zhenxia.) | Zhao, Pengfei (Zhao, Pengfei.) | Yang, Shifeng (Yang, Shifeng.) | Zhuang, Lihui (Zhuang, Lihui.) | Ding, Heyu (Ding, Heyu.) | Qiu, Xiaoyu (Qiu, Xiaoyu.) | Gao, Bin (Gao, Bin.) | Liu, Youjun (Liu, Youjun.) | Gong, Shusheng (Gong, Shusheng.) | Wang, Guopeng (Wang, Guopeng.) | Wang, Zhenchang (Wang, Zhenchang.) | Wang, Ximing (Wang, Ximing.)

Indexed by:

Scopus SCIE

Abstract:

This study aimed to investigate the effect of the transverse sinus (TS) stenosis (TSS) position caused by arachnoid granulation on patients with venous pulsatile tinnitus (VPT) and to further identify the types of TSS that are of therapeutic significance for patients. Multiphysics interaction models of six patients with moderate TSS caused by arachnoid granulation and virtual stent placement in TSS were reconstructed, including three patients with TSS located in the middle segment of the TS (group 1) and three patients with TTS in the middle and proximal involvement segment of the TS (group 2). The transient multiphysics interaction simulation method was applied to elucidate the differences in biomechanical and acoustic parameters between the two groups. The results revealed that the blood flow pattern at the TS and sigmoid sinus junction was significantly changed depending on the stenosis position. Preoperative patients had increased blood flow in the TSS region and TSS downstream where the blood flow impacted the vessel wall. In group 1, the postoperative blood flow pattern, average wall pressure, vessel wall vibration, and sound pressure level of the three patients were comparable to the preoperative state. However, the postoperative blood flow velocity decreased in group 2. The postoperative average wall pressure, vessel wall vibration, and sound pressure level of the three patients were significantly improved compared with the preoperative state. Intravascular intervention therapy should be considered for patients with moderate TSS caused by arachnoid granulations in the middle and proximal involvement segment of the TS. TSS might not be considered the cause of VPT symptoms in patients with moderate TSS caused by arachnoid granulation in the middle segment of the TS.

Keyword:

biomechanical multiphysics interaction computation transverse sinus stenosis arachnoid granulation pulsatile tinnitus

Author Community:

  • [ 1 ] [Mu, Zhenxia]Shandong First Med Univ, Shandong Prov Hosp, Dept Radiol, Jinan 250021, Peoples R China
  • [ 2 ] [Yang, Shifeng]Shandong First Med Univ, Shandong Prov Hosp, Dept Radiol, Jinan 250021, Peoples R China
  • [ 3 ] [Zhuang, Lihui]Shandong First Med Univ, Shandong Prov Hosp, Dept Radiol, Jinan 250021, Peoples R China
  • [ 4 ] [Wang, Ximing]Shandong First Med Univ, Shandong Prov Hosp, Dept Radiol, Jinan 250021, Peoples R China
  • [ 5 ] [Zhao, Pengfei]Capital Med Univ, Beijing Friendship Hosp, Dept Radiol, Beijing 100050, Peoples R China
  • [ 6 ] [Ding, Heyu]Capital Med Univ, Beijing Friendship Hosp, Dept Radiol, Beijing 100050, Peoples R China
  • [ 7 ] [Qiu, Xiaoyu]Capital Med Univ, Beijing Friendship Hosp, Dept Radiol, Beijing 100050, Peoples R China
  • [ 8 ] [Wang, Zhenchang]Capital Med Univ, Beijing Friendship Hosp, Dept Radiol, Beijing 100050, Peoples R China
  • [ 9 ] [Gao, Bin]Beijing Univ Technol, Coll Chem & Life Sci, Dept Biomed Engn, Beijing 100124, Peoples R China
  • [ 10 ] [Liu, Youjun]Beijing Univ Technol, Coll Chem & Life Sci, Dept Biomed Engn, Beijing 100124, Peoples R China
  • [ 11 ] [Gong, Shusheng]Capital Med Univ, Beijing Friendship Hosp, Dept Otolaryngol Head & Neck Surg, Beijing 100050, Peoples R China
  • [ 12 ] [Wang, Guopeng]Capital Med Univ, Beijing Friendship Hosp, Dept Otolaryngol Head & Neck Surg, Beijing 100050, Peoples R China

Reprint Author's Address:

  • [Wang, Ximing]Shandong First Med Univ, Shandong Prov Hosp, Dept Radiol, Jinan 250021, Peoples R China;;[Wang, Zhenchang]Capital Med Univ, Beijing Friendship Hosp, Dept Radiol, Beijing 100050, Peoples R China;;

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Source :

BIOENGINEERING-BASEL

Year: 2024

Issue: 6

Volume: 11

4 . 6 0 0

JCR@2022

Cited Count:

WoS CC Cited Count:

SCOPUS Cited Count:

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 4

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