• Complex
  • Title
  • Keyword
  • Abstract
  • Scholars
  • Journal
  • ISSN
  • Conference
搜索

Author:

Han, Yanjing (Han, Yanjing.) | Yang, Qingqing (Yang, Qingqing.) | Yang, Zeran (Yang, Zeran.) | Xia, Jun (Xia, Jun.) | Su, Tianhao (Su, Tianhao.) | Yu, Jianan (Yu, Jianan.) | Jin, Long (Jin, Long.) | Qiao, Aike (Qiao, Aike.) (Scholars:乔爱科)

Indexed by:

Scopus SCIE PubMed

Abstract:

OBJECTIVE: To investigate the relationships between upstream venous sinus stenosis and pulsatile tinnitus (PT), and to assess the correlation with diverticulum growth and the effectiveness of stent implantation. METHODS: Patient-specific geometric models were constructed using computed tomography venography images from a patient with PT, with sigmoid sinus diverticulum, and with upstream transverse sinus stenosis, in whom stenting of the upstream sinus stenosis alone achieved complete remission of PT. Computational fluid dynamics simulation based on this patient-specific geometry was performed using commercially available finite element software (ANSYS-14) to qualitatively and quantitatively compare the flow velocity, flow rate, velocity vector, pressure, vorticity, and wall shear stress on the affected side transverse and sigmoid sinuses, before and after stent implantation. RESULTS: Stenting improved the flow direction and magnitude. After stenting, the flow pattern became smoother and more regular. High-speed blood flow at the level of the diverticulum neck was confined to a smaller area, and its direction changed from approximately perpendicular to the diverticular dome to the distal side of the diverticular neck. The diverticulum showed obvious flow reduction, with decreases of 80.7%, 68.7%, 96.1%, and 91.3% in peak velocity, inflow rate, pressure gradient, and peak vorticity, respectively. The abnormally low wall shear stress at the dome of diverticulum was eliminated. CONCLUSIONS: Our findings strongly support a major role of diverticulum stenosis before in PT development and suggest that such stenosis is a causative factor of diverticulum growth. They also confirm the effectiveness of stent implantation for the treatment of PT.

Keyword:

Stent implantation Computational fluid dynamics Sinus stenosis Pulsatile tinnitus Sigmoid sinus diverticulum

Author Community:

  • [ 1 ] [Han, Yanjing]Capital Med Univ, Beijing Friendship Hosp, Dept Intervent Radiog, Beijing, Peoples R China
  • [ 2 ] [Yang, Zeran]Capital Med Univ, Beijing Friendship Hosp, Dept Intervent Radiog, Beijing, Peoples R China
  • [ 3 ] [Su, Tianhao]Capital Med Univ, Beijing Friendship Hosp, Dept Intervent Radiog, Beijing, Peoples R China
  • [ 4 ] [Yu, Jianan]Capital Med Univ, Beijing Friendship Hosp, Dept Intervent Radiog, Beijing, Peoples R China
  • [ 5 ] [Jin, Long]Capital Med Univ, Beijing Friendship Hosp, Dept Intervent Radiog, Beijing, Peoples R China
  • [ 6 ] [Yang, Qingqing]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing, Peoples R China
  • [ 7 ] [Xia, Jun]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing, Peoples R China
  • [ 8 ] [Qiao, Aike]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing, Peoples R China

Reprint Author's Address:

  • 乔爱科

    [Jin, Long]Capital Med Univ, Beijing Friendship Hosp, Dept Intervent Radiog, Beijing, Peoples R China;;[Qiao, Aike]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing, Peoples R China

Show more details

Related Keywords:

Source :

WORLD NEUROSURGERY

ISSN: 1878-8750

Year: 2017

Volume: 106

Page: 308-314

2 . 0 0 0

JCR@2022

ESI Discipline: CLINICAL MEDICINE;

ESI HC Threshold:190

CAS Journal Grade:3

Cited Count:

WoS CC Cited Count: 45

SCOPUS Cited Count: 49

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 11

Online/Total:494/10598782
Address:BJUT Library(100 Pingleyuan,Chaoyang District,Beijing 100124, China Post Code:100124) Contact Us:010-67392185
Copyright:BJUT Library Technical Support:Beijing Aegean Software Co., Ltd.