Modifying　agents　2,2-Bis(4-glycidyloxyphenyl)　propane　(2BPE)　and　dibutyl　phthalate　(DBP)　were　selected　to　enhance　the　compatibility.　By　using　molecular　simulation　software　(Materials　Studio,　MS),　nine　systems　were　constructed,　including　molecular　models　of　aged　asphalt　and　WVO　monomers　with　2BPE　and/or　DBP.　The　solubility　parameters,　Flory-Huggins　parameters,　and　interaction　energies　of　these　systems　were　calculated　to　determine　the　impact　of　2BPE　and　DBP　on　the　compatibility　of　WVO　and　aged　asphalt.　Results　showed　that　the　addition　of　2BPE　and　DBP　reduced　the　difference　in　the　solubility　parameters　between　WVO　and　aged　asphalt,　thus　improving　the　compatibility　between　WVO　and　aged　asphalt.　Additionally,　using　a　combination　of　2BPE　and　DBP　in　both　aged　asphalt　and　rejuvenator　was　found　to　be　more　effective　than　using　either　2BPE　or　DBP　alone.　Finally,　it　was　determined　that　evaluating　the　compatibility　of　WVO　and　aged　asphalt　using　Van　der　Waals　potential　and　non-bonding　energy　as　evaluation　indicators　was　more　accurate　than　using　electrostatic　potential　energy.