In　order　to　reduce　the　Pt　loading　and　atom　utilization　of　Pt-supported　catalysts,　TiO2-CNT　composite　support　was　prepared　from　carboxylated　multi-walled　carbon　nanotubes　(MWCNT)　and　tetrabutyl　titanate　via　sol-gel　method,　and　its　surface　was　introduced　a　large　number　of　oxygen　vacancy　(OV)　defects　by　high　temperature　heat　treatment.　An　electrocatalyst　Pt　SA/TiO2(OV)-CNT　anchored　by　a　composite　support　with　oxygen　vacancy　defects　was　then　prepared　by　deposition-precipitation　of　Pt　single-atom　(Pt　SA)　on　TiO2(OV)-CNT,　characterized　by　XRD,　electron　paramagnetic　resonance　spectroscopy　(EPR),　HAADF-STEM　and　XPS,　and　evaluated　by　standard　three-port　electrolytic　cell　for　its　electrochemical　performance.　The　results　showed　that　oxygen　vacancy　defects　were　successfully　introduced　onto　TiO2-CNT　and　Pt　SA　was　anchered　in　the　TiO2(OV)-CNT　lattice,　with　charge　transfer　between　the　two　forming　strong　metal-support　interactions.　Pt　SA/TiO2(OV)-CNT　exhibited　a　half-wave　potential　of　0.804　V,　a　mass　activity　(MA)　of　451.24　A/g(Pt),　and　a　Tafel　slope　of　63.75　mV/dec　at　0.90　V.　During　oxygen　reduction　(ORR)　operation　for　10000　s,　the　normalized　current　decreased　by　17%,　showing　better　ORR　dynamics.　Pt　SA/TiO2(OV)-CNT　showed　high　catalytic　activity　with　lower　Pt　loading　(mass　fraction　1.13%),　due　to　the　strong　anchoring　effect　of　oxygen　vacancy　on　Pt　SA　and　the　protective　effect　of　TiO2　film　on　CNT.　©　2024　Fine　Chemicals.　All　rights　reserved.