This　paper　validates　the　effectiveness　of　the　modeling　approach　based　on　the　finite　element　analysis　of　shaking　table　tests,　establishing　finite　element　models　for　both　a　base-isolated　structure　and　a　hybrid　base-isolated　structure　designed　to　address　overturning　issues　in　the　diesel　engine　building　of　a　nuclear　power　plant.　By　using　the　Incremental　Dynamic　Analysis　(IDA)　method,　a　fragility　analysis　of　the　overturning　resistance　was　conducted　for　both　isolation　systems.　This　study　demonstrates　that　the　hybrid　base　isolation　scheme,　which　incorporates　additional　dampers,　effectively　enhances　the　structure＇s　overturning　resistance　and　reduces　the　probability　of　failure.　When　evaluating　the　seismic　fragility　of　the　structure　by　using　the　TP　value,　which　is　related　to　the　tensile　stress　of　the　isolation　bearings,　as　a　damage　index,　the　results　are　more　conservative　compared　with　those　obtained　by　using　shear　strain　(gamma).　This　highlights　the　importance　of　improving　the　tensile　capacity　of　the　isolation　bearings　in　structural　design.　Furthermore,　fragility　assessment　using　gamma　as　a　damage　index　can　provide　design　references　for　the　collision　limit　of　the　isolation　moat　in　the　base-isolated　structure　of　the　diesel　engine　building　in　nuclear　power　plants.