To　study　dynamic　response　of　high-speed　slide　rail　with　track　irregularity　excitation,　according　to　the　vehicle　dynamic　and　track　dynamic　theory,　a　sled-track　dynamic　analysis　model　of　the　high-speed　track　system　is　established.　Sled-track　dynamic　responses　under　different　speeds　and　irregularity　excitations　are　analyzed　and　calculated.　Effect　on　sled-track　dynamic　response　by　regularity　of　high-speed　slide　rail　is　discussed　quantitatively.　Results　show　that　the　peak　vicissitude　acceleration　is　up　to　5.1　m/s2　when　the　high-speed　sled　slides　at　the　speed　of　700　m/s.　When　the　sliding　speed　is　700　m/s,　the　vibration　acceleration　of　the　sled　is　8　times　than　that　of　100　m/s.　To　avoid　excessive　vibration,　the　high-speed　sled　irregularity　amplitude　must　be　less　than　2　mm.