Graphene　oxide　(GO)　is　one　typical　two-dimension　structured　and　oxygenated　planar　molecular　material.　Researchers　across　multiple　disciplines　have　paid　enormous　attention　to　it　due　to　the　unique　physiochemical　properties.　However,　models　used　to　describe　the　structure　of　GO　are　still　in　dispute　and　ongoing　to　update.　And　currently,　synthesis　methods　for　mass　production　are　seemingly　abundant　but　in　fact,　dominated　by　a　few　core　methodologies.　To　update　with　the　state-of-an　opinions　and　progresses,　herein　we　present　a　mini　critical　review　regarding　the　synthesis　of　GO　as　well　as　its　models　and　simulations　of　structure.　Also,　we　discuss　the　perspectives.　(C)　2019　The　Chemical　Industry　and　Engineering　Society　of　China,　and　Chemical　Industry　Press　Co.,　Ltd.　All　rights　reserved.