The　KIT-6-templating　and　polyvinyl　alcohol-protected　NaBH4　reduction　methods　were　adopted　to　prepare　the　mesoporous　manganese　oxide　(meso-MnOy)　and　its　supported　Co,　Pt,　and　PtxCo　catalysts,　respectively.　Numerous　techniques　were　used　to　characterize　the　physicochemical　properties　of　the　materials.　Catalytic　performance　of　the　samples　was　evaluated　for　methanol　combustion.　All　of　the　samples　possessed　a　three-dimensionally　ordered　mesoporous　structure　and　a　surface　area　of　94-110　m(2)/g.　The　Co,　Pt,　and　PtxCo　nanoparticles　(NPs)　with　an　average　size　of　2.2-3.0　nm　were　uniformly　dispersed　on　the　surface　of　meso-MnOy.　The　0.70　wt%　Pt2.42Co/meso-MnOy　sample　performed　the　best:　the　T-50%　and　T-90%　(temperatures　required　for　achieving　methanol　conversions　of　50　and　90%,　respectively)　were　50　and　86　degrees　C　at　a　space　velocity　of　80,000　mL/(g　h).　The　partial　deactivation　of　the　0.70Pt(2.42)Co/meso-MnOy　sample　due　to　water　vapor　or　carbon　dioxide　introduction　was　reversible.　It　is　concluded　that　the　excellent　catalytic　activity　of　0.70　wt%　Pt2.42Co/meso-MnOy　was　associated　with　its　highly　dispersed　Pt2.42Co　alloy　NPs,　high　adsorbed　oxygen　species　concentration,　good　low-temperature　reducibility,　and　strong　interaction　between　Pt2.42Co　alloy　NPs　and　meso-MnOy.