In　order　to　automatically　detect　the　print　defects　of　PET　board　of　a　kind　of　biochip,　integrated　electro-mechanical　method　was　employed　to　design　the　experimental　platform　for　the　recognition　and　marker　of　PET　board,　therefore　the　automatic　control　of　mechanical　inspection　system　was　realized;　CCD　sensor　was　used　to　get　the　image　of　PET　board,　and　specific　computer　software　was　developed　to　achieve　the　image　processing　and　recognition　of　PET　board;　thus,　the　automatic　inspection　system　of　print　quality　of　biochips　was　constructed.　Practical　results　indicated　that　this　system　can　precisely　and　effectively　achieve　real-time　detection.　©　2008　IEEE.