In　Wankel　rotary　engine　(WRE),　high　mainstream　velocity　in　combustion　chamber　blocks　flame　propagating　to　the　end　of　combustion　chamber,　which　causes　high　emissions　and　low　combustion　efficiency　due　to　unburned　mixtures.　To　solve　this　problem,　a　three-dimensional　dynamic　simulation　model　of　a　hydrogen-gasoline　blends　fueled　WRE　is　built　and　validated.　The　in-cylinder　mixture　formation　and　combustion　process　are　investigated　under　different　hydrogen　injection　timing　(HIT)　and　duration　(HID)　conditions.　The　study　results　show　that　the　concentration　of　hydrogen　distributed　between　the　spark　plug　region　and　rear　combustion　chamber　increases　with　retarded　HIT　and　extended　HID.　Faster　flame　speeds　are　obtained　for　HIT　of　110　degrees　CA　BTDC　and　HID　of　40　degrees　CA.　At　a　fixed　HID　of　20　degrees　CA,　compared　with　HITs　of　210　and　160　degrees　CA　BTDC,　the　peak　in-cylinder　pressures　for　HIT　of　110　degrees　CA　BTDC　are　increased　by　14.3%　and　6.8%,　respectively.　At　a　fixed　HIT　of　110　degrees　CA　BTDC,　the　peak　in-cylinder　pressure　in　HID　of　40　degrees　CA　is　52.3%　and　9.21%　higher　than　HIDs　of　20　and　30　degrees　CA.　The　highest　in-cylinder　pressure　is　achieved　with　the　hydrogen　injection　strategy　that　HIT　of　110　degrees　CA　BTDC,　HID　of　40　degrees　CA.　However,　as　the　temperature　increases　with　pressure,　nitrogen　oxide　emissions　are　also　increased　with　retarded　HIT　and　extended　HID　obviously.　Considering　the　lowest　carbon　monoxide　is　achieved　and　the　unburned　zone　in　the　rear　region　of　combustion　chamber　is　eliminated　in　HIT　of　110　degrees　CA　BTDC,　of　40　degrees　CA.　The　hydrogen　direct　injection　strategy　that　HIT　of　110　degrees　CA　BTDC,　HID　of　40　degrees　CA　acquires　the　best　engine　performance　in　this　research.