Hot　stamping　is　an　important　manufacturing　process　for　sheet　metal　parts.　However,　it　is　easy　to　produce　defects　such　as　thinning　and　cracking　in　the　drawing　area　during　the　stamping　process.　In　this　paper,　the　finite　element　solver　ABAQUS/Explicit　was　used　to　establish　the　numerical　model　of　the　magnesium　alloy　hot-stamping　process.　The　stamping　speed　(2　similar　to　10　mm/s),　the　blank-holder　force　(3　similar　to　7　kN),　and　the　friction　coefficient　(0.12　similar　to　0.18)　were　selected　as　the　influencing　factors.　Taking　the　maximum　thinning　rate　obtained　through　simulation　as　the　optimization　objective,　the　response　surface　methodology　(RSM)　was　applied　to　optimize　the　influencing　factors　in　sheet　hot　stamping　at　a　forming　temperature　of　200　degrees　C.　The　results　showed　that　the　maximum　thinning　rate　of　sheet　metal　was　most　influenced　by　the　blank-holder　force,　and　the　interaction　between　the　stamping　speed　and　the　blank-holder　force/friction　coefficient　had　a　great　influence　on　the　maximum　thinning　rate.　The　optimal　value　of　the　maximum　thinning　rate　of　the　hot-stamped　sheet　was　7.37%.　Through　the　experimental　verification　for　the　hot-stamping　process　scheme,　the　maximum　relative　error　between　the　simulation　and　the　experimental　results　was　8.72%.　This　proves　the　accuracy　of　the　established　finite　element　model　and　the　response　surface　model.　This　research　provides　a　feasible　optimization　scheme　for　the　analysis　of　the　hot-stamping　process　of　magnesium　alloys.