Nanofiltration　has　been　playing　an　important　role　in　water　purification,　in　which　the　developments　of　novel　membrane　materials　and　modules　are　among　significant.　Herein,　a　metal-organic　framework　(MOFs)　hybrid　membrane,　ZIF-8/PSS　was　fabricated　on　a　tubular　alumina　substrate　through　a　layer-by-layer　self-assembly　technique.　ZIF-8　particles　in　situ　grow　into　PSS　layers　to　improve　their　compatibility　and　dispersion,　thereby　getting　high　quality　membrane,　which　was　loaded　into　a　steel　tubular　module　for　nano-filtrating　dyes　from　water.　Under　optimized　conditions,　it　shows　outstanding　nanofiltration　properties　toward　methyl　blue,　with　the　flux　of　210　Lm(-2)　h(-1)　MPa-1　and　the　rejection　of　98.6%.　Furthermore,　the　good　pressure　resistance　ability　and　running　stability　of　the　membrane　were　revealed,　which　can　be　attributed　to　use　the　ceramic　substrate　and　the　inherent　stability　of　ZIF-8.　This　work　thus　illustrates　a　simple　approach　for　fabricating　MOFs　hybrid　membranes　on　tubular　ceramic　substrates,　having　great　potential　for　industrial　applications.　(c)　2015　American　Institute　of　Chemical　Engineers　AIChE　J,　62:　538-546,　2016