Skyrmions　with　topologically　nontrivial　spin　textures　are　promising　information　carriers　in　next-generation　ultralow　power　consumption　and　high-density　spintronic　devices.　To　promote　their　further　development　and　utilization,　the　search　for　new　room　temperature　skyrmion-hosting　materials　is　crucial.　Considering　that　most　of　the　previous　skyrmion-hosting　materials　are　noncollinear　magnets,　here,　the　detection　of　the　topological　Hall　effect　(THE)　and　the　discovery　of　skyrmions　at　room　temperature　are　first　reported　in　a　centrosymmetric　complex　noncollinear　ferromagnet　NdMn2Ge2.　Below　330　K,　the　compound　can　host　stable　Bloch-type　skyrmions　with　about　75　nm　diameter　in　a　wide　window　of　magnetic　field　and　temperature,　including　zero　magnetic　field　and　room　temperature.　Moreover,　the　skyrmions　can　induce　a　giant　topological　Hall　effect　in　a　wide　temperature　range　with　a　maximum　value　of　-2.05　mu　Omega　cm.　These　features　make　the　compound　attractive　for　both　fundamental　research　and　potential　application　in　novel　spintronic　devices.