Different　thermal　preferences　from　occupants　in　a　shared　space　must　be　satisfied　simultaneously.　For　a　ventilated　room　with　multiple　air　supply　inlets,　differentiated　thermal　environment　parameters　can　be　maintained　in　different　subzones　by　liberating　the　unified　air　supply　parameter　adjustment　from　all　the　air　supply　inlets　and　subsequently　adopting　independent　adjustment　of　different　groups　of　air　supply　inlets　near　different　subzones.　In　this　study,　the　achievable　difference　level　of　thermal　environment　was　investigated　numerically　based　on　the　stratum　ventilation.　Primarily,　the　effect　of　independently　regulating　the　air　supply　directions　and　velocities　from　two　inlet　groups　on　the　difference　in　the　local　thermal　environment　between　subzones　was　analyzed.　The　position　of　occupants　and　heat　distribution　were　considered　as　the　influencing　factors.　Further,　the　predicted　mean　vote　(PMV)　index　was　utilized　to　evaluate　the　cool　or　warm　degree　of　the　local　thermal　environment　while　the　draught　rate　(DR)　and　percentage　dissatisfied　(PD)　indices　were　utilized　to　evaluate　the　local　thermal　discomfort.　The　results　obtained　indicated　that　regulating　air　supply　direction　significantly　affected　the　differentiated　thermal　environment,　with　the　achievable　Delta　PMV　between　subzones　up　to　1.46.　Moreover,　the　increase　in　air　supply　velocity　based　on　the　appropriate　air　supply　direction　further　expanded　the　Delta　PMV.　In　addition,　the　change　in　heat　source　position　resulted　in　a　Delta　PMV　decrease　of　0.36.　No　strong　draught　risk　and　local　thermal　discomfort　caused　by　the　vertical　temperature　difference　were　observed.　This　study　is　expected　to　provide　guidance　for　the　maintenance　of　demand-oriented　zoning　thermal　environment.