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Author:

Niu, Yumiao (Niu, Yumiao.) | Du, Tianming (Du, Tianming.) | Liu, Youjun (Liu, Youjun.) (Scholars:刘有军)

Indexed by:

Scopus SCIE

Abstract:

Bone has a special structure that is both stiff and elastic, and the composition of bone confers it with an exceptional mechanical property. However, bone substitute materials that are made of the same hydroxyapatite (HA) and collagen do not offer the same mechanical properties. It is important for bionic bone preparation to understand the structure of bone and the mineralization process and factors. In this paper, the research on the mineralization of collagen is reviewed in terms of the mechanical properties in recent years. Firstly, the structure and mechanical properties of bone are analyzed, and the differences of bone in different parts are described. Then, different scaffolds for bone repair are suggested considering bone repair sites. Mineralized collagen seems to be a better option for new composite scaffolds. Last, the paper introduces the most common method to prepare mineralized collagen and summarizes the factors influencing collagen mineralization and methods to analyze its mechanical properties. In conclusion, mineralized collagen is thought to be an ideal bone substitute material because it promotes faster development. Among the factors that promote collagen mineralization, more attention should be given to the mechanical loading factors of bone.

Keyword:

bone biomaterial collagen biomechanics mineralization

Author Community:

  • [ 1 ] [Niu, Yumiao]Beijing Univ Technol, Fac Environm & Life, Beijing 100124, Peoples R China
  • [ 2 ] [Du, Tianming]Beijing Univ Technol, Fac Environm & Life, Beijing 100124, Peoples R China
  • [ 3 ] [Liu, Youjun]Beijing Univ Technol, Fac Environm & Life, Beijing 100124, Peoples R China

Reprint Author's Address:

  • [Du, Tianming]Beijing Univ Technol, Fac Environm & Life, Beijing 100124, Peoples R China;;[Liu, Youjun]Beijing Univ Technol, Fac Environm & Life, Beijing 100124, Peoples R China;;

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Source :

JOURNAL OF FUNCTIONAL BIOMATERIALS

Year: 2023

Issue: 4

Volume: 14

4 . 8 0 0

JCR@2022

Cited Count:

WoS CC Cited Count: 37

SCOPUS Cited Count: 43

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 3

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