Pt-based　commercial　catalysts　tend　to　be　poisoned　by　chlorine　species　in　the　oxidation　of　chlorinated　volatile　organic　compounds　(CVOCs),　which　greatly　limits　their　wide　applications.　It　is　vital　to　develop　the　active　catalysts　with　good　chlorine　resistance.　In　the　present　work,　the　novel　supported　ternary　metallic　catalysts　(PtSnM/　CeO2;　M　=　Mn,　W,　Nb)　with　the　closely　coupled　multi-active　sites　show　good　catalytic　performance　and　excellent　chlorine　resistance　for　the　oxidation　of　toluene　and　chlorobenzene　(CB),　and　can　effectively　inhibit　formation　of　the　toxic　chlorine-containing　by-products.　The　catalytic　activity　for　toluene　oxidation　in　the　mixed　VOCs　system　follows　the　sequence:　PtSnMn/CeO2　＞　PtSnW/CeO2　&　AP;PtSnNb/CeO2　＞　PtSn/CeO2　＞　Pt/CeO2.　The　change　of　the　electron　structure　around　Pt　results　in　the　difference　in　adsorption　capacity　of　toluene　and　CB.　The　C-Cl　bond　is　first　dissociated　at　the　Bronsted　acid　sites,　and　the　non-chlorinated　organic　compounds　are　oxidized　at　the　Pt　sites　that　contact　with　the　acid　sites　in　the　proximity.　Additional　water　provides　sufficient　protons　to　react　with　Cl　species,　enhancing　the　desorption　amount　of　HCl;　furthermore,　the　water　also　reacts　with　the　adsorbed　oxygen　to　generate　new　oxygen　species,　which　participates　in　the　oxidation　of　VOCs,　so　as　to　accelerate　the　removal　of　Cl　species　on　the　catalyst　surface　and　reduce　the　more　toxic　polychlorine　by-products.　This　work　is　helpful　for　developing　the　supported　noble　metal　catalysts　with　good　chlorine-resistant　performance　in　the　oxidation　of　multicomponent　VOCs　under　the　actual　industrial　conditions.